Drug Discovery Using CRISPR Technology Certification Course
Drug Discovery Using CRISPR Technology
Many of the therapeutic drug candidates fail through their clinical trials. It takes millions and billions of years to develop a new drug and bring it into existence. Mostly all drug discovery process starts with basic scientific research and involves lots of steps before new therapeutics are approved for clinical use. Each pharmaceutical company aims at approaching the discovery and development of new drugs differently; the major steps common to most preclinical processes are target identification and validation, high-throughput compound screening, hit validation and lead drug candidate optimization.
Any kind of novel research methodology in drug discovery could save many lives and money. CRISPR-Cas9, the recently-harnessed genome editing technology, is quite a candidate in accelerating progress through all of these steps!
CRISPR-Cas9 system, derived from bacteria’s adaptive immune system, is primarily a nuclease complex, which induces lesions in DNA. Thus technology is used as a bio-engineering tool that enables genetic editing to be propagated in protein expression, having an impact on the health of the cell and the person as a whole
CRISPR-Cas9 has immense applications as a drug discovery tool. The therapeutic drug's mechanism of action is to alter the function of the body’s workforce: the proteins. The main question to create such a drug is to determine which proteins should be targeted. Like which proteins actually matter for the occurrence of let’s say cancer. In order to find these disease-relevant genes and proteins, researchers are using CRISPR-Cas9 to systematically inactivate, or knock out, the ~20,000 protein-coding genes found in humans. In other words, this is called the “genome-wide screen.”
Testing the efficacy and pathophysiology of a particular drug is an essential step in drug development. This might require exact disease models to mimic the actual condition. CRISPR-Cas9 system can specifically knock-in, knock-out, modify target genes, thus generating an appropriate animal/disease model for drug testing. As such, CRISPR technologies specificity to identify which parts of the protein are important for function or disrupt the drug’s ability to engage its target make this technology an indispensable tool for therapeutic development and precision medicine as well.
Importance/benefits of the Drug Discovery Using CRISPR Technology Course:
This course helps one to develop their knowledge and understanding of how drugs and medicines are discovered, the steps and the technology involved. In addition to these, some research methods are also dealt with, which are key to understanding modern drug discovery and development. Attendees not only get to learn about the major aspects of the drug discovery process, starting with target selection, to compound screening to designing lead candidates but also can increase their understanding of the various drug discovery tools and methods that are used for finding, identifying and designing a new drug.
Drug companies are always aiming to attract and recruit the best scientists. What they look for is a solid university track record, good publications, evidence of good communication, team, and leadership skills, and most importantly, sound knowledge of the subject and the recent updates in the related area. Attendees looking at making a career in this field will definitely be benefited from this course.
One of the major focus of drug discovery in recent years has been the generation of more physiologically relevant models, which could provide a better correlation to the clinical setting and thereby reduce candidate drug attrition. CRISPR/Cas9, as discussed in this course, represents a significant opportunity in this area, which is used to efficiently and precisely edit a cell’s DNA to generate both in vitro and in vivo models.
CRISPR/Cas9 technology is soon going to become an indispensable part of genome editing. These nature's very own tools are creating wonders when it comes to gene cutting, nicking, knockin, knockout as well as expression activation and inhibition. Attendees taking up a basic and an advanced course in this technology will be able to understand the importance of this technology in drug discovery. This course bridges the gap between these two processes and points out the precise genome editing applications in various steps of drug development such as in animal model creation and in precision medicine.
Eligibility for Drug Discovery Using CRISPR Technology Course:
- Students in their B.Sc / B.Tech / M.Sc / M.Tech who aspire to work on cutting-edge research technologies used in drug discovery.
- Aspiring scientists who look forward to innovating novel methods to develop new drugs with advanced technologies.
- Science enthusiasts who like to stay updated about the recent research updates using the most talked-about processes.
- Any candidate who is looking for a career in the pharmaceutical industry.
Career Opportunities after Drug Discovery Using CRISPR Technology Course:
The drug discovery industry holds a wide range of research opportunities and varied tracks for career advancement while staying focused on high-quality research just like academia. Pharmaceutical companies have ongoing needs for biochemists, organic chemists, cellular biologists, molecular biologists, microbiologists, genetic biologists, and in vivo pharmacists at both the basic and applied research levels.
As already mentioned, the creation of new drugs is a risky, time-consuming and expensive business. So it may take up to more than 10 years to bring a new drug to market, which in turn requires the effort of thousands of people from many scientific disciplines. In such a huge and complex organization, young scientists have the option to select from many different career options. The pharmaceutical industry is no longer limited to biology and chemistry, but can also offer long-term careers in various disciplines and subdisciplines. In fact, "cross-functional" scientists are actually becoming an increasingly valuable commodity. Systems biology is beginning to take hold, and this is going to increase the opportunity for scientists with multiple degrees, pharmacology with genomics, information technology with biology, etc.
FAQs- Drug Discovery Using CRISPR Technology Certification Course
- What is an Online Self Learning Course?
An Online Self Learning Certification Course means you can log in any time and study at your own pace. However, you must watch 90% of all the lessons to proceed to the next lesson and if you want a Hard copy certificate you must clear the evaluation test, which will be available at the end of the course.
- How to get started with the Drug Discovery Using CRISPR Technology self-learning course?
Once you enroll for the awesome course, You will get the activation email almost immediately. start and finish the course at your own pace! Start learning whenever you can. There is no need to bend your schedule.
- How to unlock the next lesson of the Drug Discovery Using CRISPR Technology course?
Once you master a session hit the Complete and Continue button on the top to begin your next session. Make sure you don't skip through! Unless you complete the current lesson you cannot proceed to the next lesson
- What is the time limit to complete the course?
Unlimited access until you decide to complete the course. But once you have given your certification test, the course ends. If you fail in the test, you can revise the course again
- How do I evaluate myself?
Time to test all the knowledge you have gained. Take the test at the end of the course and evaluate yourself. Every Self Learning Course has a test at the end.
- How to get the hard copy certificate after the Drug Discovery Using CRISPR Technology Course?
To avail, the hard copy certificate, Take the test at the end of the course. Clearing the test ( with a minimum of 40%) will earn you the certificate. The certificate will be sent to your doorstep. Now you know not to skip through the course.
- Whom do I contact for any further queries?
- Will BioTecNika Provide any Job Guarantee / Assistance?
No, BioTecNika does not provide any Job Assistance or Guarantee. However you are free to apply for a Job on BioTecNika’s Job Portal and certainly, employers will give more weightage to you due to the reputation of BioTecNika and the Knowledge possessed by you after the course. A Certification from BioTecNika is well respected and honored by most of the employers in the industry